Creatine5000® by EVLution Nutrition is a no-frills dietary supplement designed to deliver a precise 5,000 mg dose of creatine monohydrate per serving. Creatine monohydrate is the most extensively studied and scientifically supported form of creatine, with decades of research confirming its efficacy in improving strength, power output, and lean muscle mass during high-intensity resistance training [1][2]. This product aligns with standard maintenance dosing protocols, making it suitable for athletes and active individuals seeking performance enhancement without the need for a loading phase.
The formulation contains only creatine monohydrate in its unflavored form, ensuring maximum purity and minimizing potential gastrointestinal or allergenic concerns. Given that creatine monohydrate is already highly bioavailable and cost-effective, this product avoids the use of proprietary blends or alternative forms that lack equivalent evidence. Its simplicity supports consistent daily use, which is key to achieving and maintaining elevated intramuscular creatine levels over time [3].
Quick Summary
Full transparency is achieved: exact ingredient amount is disclosed, no proprietary blends, and only one active ingredient listed clearly on the label.
The primary ingredient, creatine monohydrate, is delivered at a clinically effective dose of 5,000 mg, which is sufficient to maintain elevated muscle creatine stores and improve high-intensity exercise performance [2][3].
Creatine monohydrate has excellent oral bioavailability and is the most well-studied form. While absorption can be slightly enhanced with insulinogenic nutrients, it is already highly effective in its standard form [3].
Suggested: 1 serving/day to reach clinical midpoint
Why Take This Product
Key Benefits
- Greater Lean Muscle Mass: Creatine promotes muscle hypertrophy over time by enabling greater training intensity and potentially stimulating satellite cell activity and myofibrillar protein synthesis [2].
- Enhanced Recovery: Evidence suggests creatine may reduce muscle damage and inflammation following intense exercise, supporting faster recovery between sessions [6].
- Potential Cognitive and Neurological Benefits: Some studies indicate creatine supplementation may support brain health, particularly in situations of metabolic stress, sleep loss, or aging, due to its role in cellular energy metabolism [6].
Who Should Take This
Potential Side Effects
Ingredient Breakdown
This product contains only one ingredient: creatine monohydrate. It is classified as the primary active compound and is present in a clinically effective dose. No supporting ingredients are included, which enhances transparency and reduces the risk of unnecessary additives or allergens.
Primary Ingredients
Creatine Monohydrate
Increases phosphocreatine stores to enhance ATP regeneration during high-intensity exercise
Dose of 5,000 mg falls within the upper end of the clinically studied maintenance range (3–5 g/day). No loading phase required. Superior to other forms in terms of evidence and cost-effectiveness [3].
Creatine monohydrate is the gold-standard form of creatine, supported by extensive research demonstrating improvements in strength, power, muscle mass, and exercise capacity. It is highly bioavailable and safe for long-term use in healthy individuals.
Practical Recommendations
- Consistent Daily Dosing: Take one serving (5,000 mg) daily, with or without food. While a loading phase (20 g/day for 5–7 days) can accelerate saturation, it is not required when using a daily 5 g dose.
- Pair With Carbohydrates Or Protein: Consuming creatine with a meal containing carbohydrates or protein may enhance uptake due to insulin-mediated transport, though it remains effective when taken alone [2].
- Stay Hydrated: Ensure adequate daily fluid intake to support cellular hydration and minimize any risk of cramping or gastrointestinal discomfort.
Is it Safe?
Creatine monohydrate is one of the most well-researched supplements available, with an excellent safety profile in healthy populations. Long-term studies show no adverse effects on renal, hepatic, or cardiovascular function at doses up to 10 g/day [4][5]. However, medical consultation is advised for those with pre-existing kidney disease.
Safety & Considerations
- Pre-Existing Condition: Individuals with kidney disorders should consult a healthcare provider before use, despite lack of evidence for harm in healthy users.
The Science
The efficacy of Creatine5000® is driven entirely by its 5,000 mg dose of creatine monohydrate, which meets or exceeds the typical maintenance dose used in clinical research. This dose reliably increases intramuscular creatine stores and supports performance benefits without requiring a loading phase [2].
Demonstrates that creatine supplementation enhances high-intensity exercise performance in both males and females.
Confirms creatine increases muscle performance in short-duration, high-intensity resistance exercise; outlines typical dosing strategies.
Concludes that creatine monohydrate is more bioavailable, effective, and better studied than other forms; novel forms offer no added benefit.
Shows no adverse effects on renal function in healthy sedentary males taking ~10 g/day for 3 months.
Supports safety of creatine in long-term use with no significant organ toxicity observed.
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