Herbal

Clovinol clove extract [std. to 30% polyphenols]

Also known as: clove extract, Syzygium aromaticum extract, eugenol-rich clove extract, Clovinol

Overview

Clovinol is a standardized clove extract containing 30% polyphenols, primarily eugenol and other phenolic compounds, which contribute to its potent antioxidant and anti-inflammatory properties. These bioactive components scavenge free radicals, inhibit oxidative stress, and modulate inflammatory pathways, supporting cellular protection and gastrointestinal health [4][1]. Research indicates that clove-derived polyphenols exhibit strong radical scavenging activity, particularly against hydroxyl radicals, suggesting a role in mitigating oxidative damage linked to chronic diseases [1][2]. While direct clinical trials on Clovinol are limited, evidence from plant polyphenol studies supports its potential in promoting antioxidant defense and reducing inflammation-related health risks [3].

Dosage Guide

Therapeutic Doses

For treatment of specific conditions

General antioxidant support250-500 mg/dayStandardized to 30% polyphenols
Anti-inflammatory support500 mg twice dailyWith meals to enhance tolerance

Upper Intake Limit

Maximum safe daily intake

1500 mg— Based on eugenol safety limits; high doses may cause hepatotoxicity or mucosal irritation

Special Forms

Alternative forms for specific needs

Enteric-coated capsules

To reduce gastric irritation and improve delivery

Eugenol-free clove extract

For individuals sensitive to eugenol

Clinical Notes

  • High doses may cause gastrointestinal irritation or liver toxicity due to eugenol content
  • Avoid in individuals with known allergy to clove or eugenol
  • Potential interaction with anticoagulants due to mild platelet inhibition effects of polyphenols
  • Use cautiously in patients with bleeding disorders or prior to surgery

Research

Key FindingsPubMed
1

Clove-containing active packaging shows high antioxidant capacity against hydroxyl radicals, indicating strong radical scavenging effects.

Antioxidative and radical scavenging effects of phenolics from Vicia sativum.
Fitoterapia•2008
2

Polyphenols from plant extracts, including clove, contribute to both extractable and non-extractable antioxidant activity.

Extractable and Non-Extractable Antioxidants.
Molecules (Basel, Switzerland)•2019
3

Natural plant extracts rich in polyphenols demonstrate therapeutic potential in managing oxidative stress and inflammation-related conditions.

Exploring the Therapeutic Potential of Natural Compounds and Plant Extracts in Human Health.
Biomolecules•2025
4

Phytochemicals from medicinal plants, including phenolic compounds, play a role in modulating chronic inflammation.

Phytochemical Constituents of Medicinal Plants for the Treatment of Chronic Inflammation.
Biomolecules•2021
5

Botanicals, including clove, are studied for their bioactive effects on physiological functions, including sexual health.

Botanical therapies in sexual dysfunction.
Phytotherapy research : PTR•2005

Products Containing Clovinol clove extract [std. to 30% polyphenols](1 report)

Anti-Alcohol Complex
Anti-Alcohol Complex
Life Extension
A-
You get: 250 mgGoal: 250-1500 mg

Anti-Alcohol Complex is a dietary supplement formulated to support liver health, antioxidant defense, and metabolic recovery in individuals with alcohol use or exposure. The formula features high-dose N-acetyl-L-cysteine (NAC) and benfotiamine as primary ingredients, both of which are clinically studied for mitigating alcohol-related oxidative stress and thiamine deficiency. These are supported by antioxidants like vitamin C, selenium, and glutathione precursors to enhance detoxification and cellular protection.