Overview
Juniper berry extract has been traditionally used in herbal medicine for its diuretic, anti-inflammatory, and antimicrobial properties. Preclinical studies suggest that juniper berry contains bioactive compounds such as monoterpenes (e.g., alpha-pinene, limonene) and flavonoids that may contribute to antioxidant and anti-inflammatory effects [1][3]. Some animal and in vitro studies indicate potential benefits in supporting urinary tract health and metabolic function, though robust clinical trials in humans are lacking. There is currently insufficient high-quality evidence to confirm efficacy for any specific health condition, and most data derive from traditional use and preliminary laboratory research [2][1].
Dosage Guide
Therapeutic Doses
For treatment of specific conditions
Upper Intake Limit
Maximum safe daily intake
10 g/day— Higher doses may cause kidney irritation; avoid long-term use
Special Forms
Alternative forms for specific needs
Not for internal use; potential dermal toxicity and nephrotoxicity
Typically standardized to monoterpene content; clinical relevance unclear
Clinical Notes
- Avoid in individuals with kidney disease or during pregnancy due to potential nephrotoxic and uterotonic effects
- Long-term or high-dose use may lead to kidney irritation or gastrointestinal upset
- Potential for herb-drug interactions with diuretics and antidiabetic medications
- Essential oil should not be ingested; may be toxic
Research
Highlights the need for rigorous evaluation of plant-based remedies, using juniper as an example of traditional use with limited clinical validation.
Reviews potential health benefits of plant extracts including juniper, emphasizing preclinical evidence over clinical data.
Discusses challenges in evaluating herbal supplements, noting that traditional use does not equate to proven efficacy.
