Herbal

Longjack extract

Also known as: Eurycoma longifolia, Tongkat Ali, Long Jack, Malaysian ginseng

Overview

Longjack extract, derived from the plant Eurycoma longifolia, is traditionally used for its potential anti-inflammatory and testosterone-enhancing properties. While some natural products have demonstrated anti-inflammatory effects in preclinical studies, specific high-quality clinical evidence for Longjack remains limited [1]. It has been explored in the context of male reproductive health and chronic prostatitis due to proposed phytotherapeutic mechanisms, though robust placebo-controlled trials are lacking to confirm efficacy [3]. The use of herbal supplements like Longjack must be approached with caution due to the potential for hepatotoxicity, as highlighted in reviews on herbal and dietary supplement-induced liver injury [4]. Currently, there is insufficient evidence to support definitive therapeutic dosing or broad health benefits.

Dosage Guide

Therapeutic Doses

For treatment of specific conditions

General supplementation100-400 mg/dayTypical range used in small clinical studies; no standardized dose established

Research

Key FindingsPubMed
1

Reviews anti-inflammatory activities of natural products, including plant extracts, though specific data on Longjack is limited.

Anti-Inflammatory Activity of Natural Products.
Molecules (Basel, Switzerland)2016
2

Highlights that while some herbal medicines are efficacious, many lack rigorous clinical testing and carry potential risks.

The efficacy of herbal medicine--an overview.
Fundamental & clinical pharmacology2005
3

Suggests phytotherapeutic agents may have anti-inflammatory effects useful in chronic prostatitis, but calls for more placebo-controlled trials.

Phytotherapy for chronic prostatitis.
Current urology reports2000
4

Reports increasing cases of herbal and dietary supplement-induced liver injury, emphasizing safety concerns with botanicals like Longjack.

Herbal and Dietary Supplement-Induced Liver Injury.
Clinics in liver disease2017
5

Discusses herbal extracts for NAFLD/NASH, but does not specifically implicate Longjack with strong evidence.

Preventive and therapeutic effects of natural products and herbal extracts on nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.
Phytotherapy research : PTR2023
6

Notes widespread use of phytotherapeutic agents for benign prostatic hyperplasia but underscores lack of conclusive efficacy data due to poor study design.

Phytotherapy in the management of benign prostatic hyperplasia.
Urology2001
7

Reviews clinical herbal toxicity, supporting the need for caution with herbal supplements due to potential adverse effects and interactions.

Clinical approach to clinical herbal toxicity.
Seminars in diagnostic pathology2009

Products Containing Longjack extract(1 report)