Hydrolyzed marine collagen peptides form the cornerstone of this product, with a 5 g dose that aligns with clinical evidence for improving skin elasticity, hydration, and joint comfort. Multiple randomized trials confirm that daily intake of 2.5–10 g of low-molecular-weight collagen peptides enhances dermal matrix synthesis and reduces osteoarthritic pain, with benefits emerging after 6–12 weeks of consistent use [1][2][3]. The Gly-Pro-Hyp tripeptide motif abundant in marine collagen is believed to drive tissue-specific bioactivity, particularly in skin and cartilage.
The inclusion of a 5 g prebiotic fiber blend (resistant dextrin and partially hydrolyzed guar gum) and a 3 g leucine-enriched essential amino acid (EAA) complex supports broader metabolic and gastrointestinal health. While these are not the headline ingredients, they contribute meaningfully to satiety, gut microbiota balance, and muscle anabolism—functions that may complement GLP-1 pathway modulation indirectly through improved metabolic signaling and gut health. However, their roles are secondary to the collagen-driven benefits.
Quick Summary
All ingredient amounts are fully disclosed with no proprietary blends, ensuring complete transparency and enabling dose evaluation.
Primary ingredient (collagen) is at a clinically effective dose for skin and joint benefits, driving high efficacy. Supporting ingredients are below or at lower end of therapeutic ranges, but contribute synergistically to gut, muscle, and antioxidant health.
Uses high-bioavailability forms: hydrolyzed collagen peptides for rapid absorption, free-form crystalline amino acids, and soluble prebiotic fibers. Polyphenol extracts are standard bioactive forms.
Generally safe profile; warnings needed for fish allergy, anticoagulant use, and gradual fiber introduction. Leucine dose is moderate and balanced with other EAAs.
Suggested: 1 serving/day to reach clinical midpoint
Why Take This Product
Key Benefits
- Joint Pain and Stiffness Reduction: Clinical trials report reduced WOMAC and VAS scores in individuals with knee osteoarthritis or activity-induced joint discomfort after 8–13 weeks of collagen supplementation [4][2]. The 5 g dose is sub-therapeutic for severe osteoarthritis (10 g/day), but effective for mild-to-moderate symptoms.
- Muscle Protein Synthesis Support: The leucine-enriched EAA blend (3 g) provides key amino acids that activate mTOR signaling. While below the therapeutic 2.5–5 g leucine dose for sarcopenia, it may still support muscle maintenance when combined with adequate protein intake [8].
Who Should Take This
Potential Side Effects
Ingredient Breakdown
Each ingredient is included for a specific physiological role: collagen for structural tissue support, prebiotic fibers for gut and metabolic health, EAAs for muscle anabolism, and polyphenol-rich botanicals for antioxidant and cardiovascular protection. Doses are selected to balance efficacy and tolerability.
Primary Ingredients
Hydrolyzed Marine Collagen Peptides
Supports skin elasticity, joint function, and connective tissue health
Bioactive peptides derived from fish collagen, rich in Gly-Pro-Hyp, shown to improve skin hydration and reduce joint pain. Enhanced absorption due to hydrolysis.
Supporting Ingredients
There are 4 supporting ingredients.
Practical Recommendations
- Consistent Daily Use: For optimal results, take one serving daily with water or a meal. Benefits for skin and joints typically emerge after 6–8 weeks of uninterrupted use.
- Pair With Balanced Diet: Combine with adequate dietary protein (1.2–1.6 g/kg/day) and hydration to maximize collagen and EAA utilization and support fiber tolerance.
- Monitor For Interactions: Exercise caution if taking anticoagulants due to polyphenol content in grape and citrus extracts. Consult a healthcare provider if managing chronic conditions or taking medications.
Is it Safe?
The formula uses well-researched, GRAS-status ingredients at moderate doses. Marine collagen is safe for pescatarians but contraindicated in fish allergy. The EAA blend avoids excessive leucine, and polyphenol doses are below levels associated with iron absorption interference. No proprietary blends enhance transparency.
Safety & Considerations
- Allergy: Contains marine collagen; not suitable for individuals with fish allergies.
- Drug Interaction: Grape and red orange extracts may interact with anticoagulants due to antiplatelet polyphenols. Use caution if on warfarin or aspirin.
- Gastrointestinal: Prebiotic fiber may cause bloating or gas if introduced too quickly. Increase intake gradually and drink plenty of water.
The Science
Efficacy is driven primarily by the 5 g hydrolyzed marine collagen dose, which meets clinical thresholds for skin and joint benefits. Supporting ingredients are included at functional but sub-therapeutic levels for their individual indications, consistent with a multi-targeted supplement strategy rather than a medical intervention.
Low-dose collagen (1,000 mg/day) improves skin hydration and elasticity after 6–12 weeks.
10 g/day collagen reduces knee pain in active adults; 5 g is sub-therapeutic but may still benefit mild symptoms.
2.5–5.0 g/day collagen hydrolysate improves skin elasticity in women aged 35–55.
Collagen peptides reduce WOMAC scores in knee osteoarthritis over 13 weeks.
Fish collagen plus vitamins improve skin and joint well-being in 90-day trial.
See grades while you shop
Get instant supplement ratings directly on iHerb. Amazon & more coming soon.
Works on iHerb now, Amazon & more coming soon
Stay updated on supplement research
Get newsletters about the latest developments in supplements and evidence-based insights.
No spam. Unsubscribe anytime.
Want another product analyzed?
Scan any supplement label for a free analysis