
This supplement combines vitamin D3 (125 mcg) and vitamin K2 (50 mcg) to support bone and cardiovascular health through synergistic action. Vitamin D3 enhances calcium absorption, while K2 directs calcium to bones and away from arteries via activation of osteocalcin and matrix Gla protein. The dose of D3 is significantly higher than typical daily recommendations, indicating a therapeutic intent for deficiency correction or maintenance in high-risk individuals.

Vital Extracts, Berberine by Solaray is a dietary supplement delivering 500 mg of berberine HCl per capsule, targeting metabolic health, glycemic control, and systemic inflammation. The formulation relies on standard berberine HCl, a well-researched alkaloid with demonstrated benefits in type 2 diabetes and weight management, though its efficacy is limited by modest oral bioavailability.
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