Overview
Ginkgo biloba extract, particularly the standardized form EGb 761, has been extensively studied for its potential cognitive and neuroprotective effects. While it does not appear to enhance cognitive function in healthy individuals, meta-analyses suggest it may help stabilize or slow cognitive decline in people with cognitive impairment, dementia, or Alzheimer's disease [3][2]. The mechanisms underlying these effects include antioxidant activity from flavonoids, improved cerebral blood flow, and neuroprotection through modulation of amyloid pathology and mitochondrial function . Ginkgo extract may also offer benefits in glaucoma due to its antioxidant and vascular protective properties . However, nootropic benefits in healthy adults are not supported by current evidence [1][2].
Dosage Guide
Therapeutic Doses
For treatment of specific conditions
Special Forms
Alternative forms for specific needs
Most studied standardized extract; contains 24% flavonoids and 6% terpene lactones
Liposomal formulation with enhanced absorption
Research
No significant cognitive enhancement from Ginkgo biloba in healthy adults under 60 years in randomized clinical trials.
Meta-analysis found no significant effect of Ginkgo biloba on memory, executive function, or attention in healthy individuals.
Standardized Ginkgo biloba extract (EGb 761) shows benefit in stabilizing or slowing cognitive decline in patients with cognitive impairment and dementia.
Ginkgo biloba extract exhibits antioxidant properties that may be beneficial in glaucoma management.
Pharmaco-economic analysis in Austria showed cost savings with EGb 761 therapy due to delayed care dependency in dementia.
Liposomal Ginkgo biloba (Ginkgosome™) shows improved absorption compared to standard extract in healthy volunteers.
EGb761 has neuroprotective mechanisms relevant to Alzheimer’s disease, though clinical efficacy remains uncertain.
Seven-day use of EGb 761 (240 mg/day) did not significantly affect bleeding time or coagulation in healthy volunteers.
